Recent Publications

2014:

  1. A viral over-expression system for the major malaria mosquito Anopheles gambiae (in press). Suzuki Y, Niu G, Hughes GL, Rasgon JL. Scientific Reports 4: 5127.
  2. Discrimination of the Plasmodium mexicanum vectors Lutzomyia stewarti and Lutzomyia vexator by a PCR-RFLP assay and Wolbachia infections. Hughes GL, Samuels SK, Shaikh K, Rasgon JL and Vardo-Zalik AM. Journal of Vector Ecology. 39: 224-227.
  3. Environmental temperature alters malaria transmission blocking by Wolbachia. Murdock CC, Hughes GL, Rasgon JL and Thomas MB. Scientific Reports 4: 3932.
  4. Transinfection: a method to investigate Wolbachia-host interactions and control arthropod-borne disease. Hughes GL and Rasgon JL. Insect Molecular Biology. 23 :141-51.
  5. Harnessing Mosquito-Wolbachia Symbiosis for vector and disease control. Bourtzis K, Dobson S, Xi Z, Rasgon JL, Calviti M, Moreira LA, Bossin H, Moretti R, Baton LA, Hughes GL, Mavingui P, Gilles J. Acta Tropica. 132S: S150-63.
  6. Targeting NAD+ Metabolism in the Human Malaria Plasmodium falciparum. O’Hara JK, Kerwin LJ, Cobbold SA, Tai J, Bedell TA, Reider PJ, Llinás M. PLoS ONE. 2014 April; 9(4):e94061 PMCID: 3991606.
  7. A transcriptional switch underlies commitment to sexual development in human malaria parasitesKafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA, Cortés A, Llinás MNature. doi: 10.1038/nature12920.
  8. A cascade of DNA-binding proteins for sexual commitment and development in PlasmodiumSinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BFC, Williams AE, Llinás M, Berriman M, Billker O, Waters AP. Nature. doi: 10.1038/nature12970.
  9. Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism. Lewis IA, Wacker M, Olszewski KL, Cobbold SA, Baska KS, Tan A, Ferdig MT, Llinás MPLoS Genetics. Jan;10(1):e1004085. Epub 2014 Jan 2.

2013:

  1. Impact of trehalose transporter knockdown on Anopheles gambiae stress adaptation and susceptibility to Plasmodium falciparum infection. Liu K, Dong Y, Huang Y, Rasgon JL and Agre P. Proceedings of the National Academy of Sciences USA. 110: 17504 – 17509.
  2. Malaria-resistant mosquitoes have a fitness advantage when fed Plasmodium falciparum-infected blood. Smith RC, Kizito CM, Rasgon JL and Jacobs-Lorena M. PLoS ONE.  8: e76097.
  3. Organ-specific splice variants of aquaporin AgAQP1 in the malaria vector Anopheles gambiae. Tsujimoto H, Liu K, Linser PJ, Agre P and Rasgon JL. PLoS ONE. 8: e75888.
  4. ANOSPEX: A stochastic spatially explicit model for studying Anopheles metapopulation dynamics. Oluwagbemi OO, Fornadel CM, Adebiyi EF, Norris DE and Rasgon JL. PLoS ONE. 8: e68040.
  5. Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways in Plasmodium falciparum. Cobbold SA, Vaughan AM, Lewis IA, Painter HJ, Camargo N, Perlman DH, Fishbaugher M, Healer J, Cowman AF, Kappe SH, Llinás M. J Biol Chem. 2013 Dec 20;288(51):36338-50. doi: 10.1074/jbc.M113.503557. Epub 2013 Oct 25.
  6. Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelli liver stage developmentLindner SE, Sartain MJ, Hayes K, Harupa A, Moritz RL, Kappe SH, Vaughan AM. Mol Microbiol.  2013 Dec 11. doi: 10.1111/mmi.12485. PMID: 24330260
  7. Pertubations of Plasmodium Puf2 expression and RNA seq of Puf2 deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibilityLindner SE, Mikolajczak SA, Vaughan AM, Moon W, Joyce BR, Sullivan WJ Jr, Kappe SH. Cell Microbiol. 2013 Jul;15(7):1266-83. doi: 10.1111/cmi.12116. PMID:23356439
  8. Total and putative surface proteomics of malaria parasite salivary gland sporozites. Lindner SE*, Swearingen KE*, Harupa A, Vaughan AM, Sinnis P, Moritz RL, Kappe SH. Mol Cell Proteomics. 2013 May;12(5):1127-43. doi: 10.1074/mcp.M112.024505. PMID:23325771.
    *Equal Contribution